Barbiturates are man-made drugs and were originally developed for medical use. Doctors used to prescribe them for people who couldn´t sleep, were depressed or anxious. However, there were so many deaths from overdosing that they are no longer used. This is a class B drug. Known As: Barbs, Downers, Blues, Reds and Sekkies. Looks Like: There are many different types of barbs. They usually come in tablet form, but can also come as ampoules, suppositories, capsules or syrup. Apparent Positive Effects: Help you relax and make you sleep Produces a drunken effect The Downside: Significant risk of overdose. A lethal dose is not much different from a normal dose. Users quickly develop tolerance and become dependent quickly Withdrawal symptoms are severe, and include irritability, nervousness, insomnia, fainting, vomiting, twitching, delirium and convulsions. Sudden withdrawal can result in death.